Development of a Multivariate Digital Biomarker of Vaccine-Induced Inflammation and its Relationship to Immunogenicity

Sekaric, Wegerich, Gendy, Guo, Ward, Goergen, Amin, Wilson, Hakim, Paramethiotis, Steinhubl

 

Vaccine-induced inflammation is detectable by identifying changes in an individual’s physiologic parameters when the pre-vaccine baseline normal variation in those parameters is known. We developed a multivariate digital biomarker that incorporates changes in multiple continuously monitored physiologic data streams, and their interactions with each other, as a more sensitive measure of the degree and duration of vaccine induced inflammation.

 

Vaccines Summit, Oct. 11-13, 2022

Transferring Process Knowledge and Protocol Structure in a Continuous Remote Patient Monitoring Program: Heart Failure to Ileostomy Clinical Use Case

Chi, Reamer, Gordon, Sarswat, Gupta, White VanGompel, Dayiantis, Morton-Jost, Ravichandran, Larimer, Victorson, Erwin, Halasyamani, Solomonides,...

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Continuous Remote Patient Monitoring: Evaluation of the Cascade Heart Failure Study Phases 1 and 2

Chi, Reamer, Gordon, Sarswat, Gupta, White VanGompel, Dayiantis, Morton-Jost, Ravichandran, Larimer, Victorson, Erwin, Halasyamani, Solomonides,...

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